Publications

Pre-prints

maskNMF: A denoise-sparsen-detect approach for extracting neural signals from dense imaging data Amol Pasarkar, Ian Kinsella, Pengcheng Zhou, Melissa Wu, Daisong Pan, Jiang Lan Fan, Zhen Wang, Lamiae Abdeladim, Darcy S Peterka, Hillel Adesnik, Na Ji, Liam Paninski bioRxiv. 2023 Sep 15:2023.09.14.557777. doi: 10.1101/2023.09.14.557777. Preprint

Recurrent pattern completion drives the neocortical representation of sensory inference Hyeyoung Shin, Mora Ogando, Lamiae Abdeladim, Severine Durand, Hannah Belski, Hannah Cabasco, Henry Loefler, Ahad Bawany, Ben Hardcastle, Josh Wilkes, Katrina Nguyen, Lucas Suarez, Tye Johnson, Warren Han, Ben Ouellette, Conor Grasso, Jackie Swapp, Vivian Ha, Ahrial Young, Shiella Caldejon, Ali Williford, Peter Groblewski, Shawn Olsen, Carly Kiselycznyk, Jerome Lecoq, Hillel Adesnik

Dissociating instructive from permissive roles of brain circuits with reversible neural activity manipulations Daniel Quintana, Hayley A. Bounds, Jennifer Brown, May Wang, Nikhil Bhatla, J. Simon Wiegert, Hillel Adesnik

Probing inter-areal computations with a cellular resolution two-photon holographic mesoscope. Lamiae Abdeladim, Hyeyoung Shin, Uday K. Jagadisan, Mora B. Ogando, Hillel Adesnik

Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing Marcus A. Triplett, Marta Gajowa, Benjamin Antin, Masato Sadahiro, Hillel Adesnik, Liam Paninski

Modeling the Diverse Effects of Divisive Normalization on Noise Correlations Oren Weiss, Hayley A. Bounds, Hillel Adesnik, Ruben Coen-Cagli.

Antagonistic inhibitory subnetworks control cooperation and competition across cortical space Daniel P. Mossing, Julia Veit, Agostina Palmigiano, Kenneth D. Miller, Hillel Adesnik

Structure and variability of optogenetic responses identify the operating regime of cortex Agostina Palmigiano, Francesco Fumarola, Daniel P. Mossing, Nataliya Kraynyukova, Hillel Adesnik, Kenneth D. Miller

Published papers

Prominent in vivo influence of single interneurons in the developing barrel cortex Yannick Bollmann, Laura Modol, Thomas Tressard, Artem Vorobyev, Robin Dard, Sophie Brustlein, Ruth Sims, Imane Bendifallah, Erwan Leprince, Vincent de Sars, Emiliano Ronzitti, Agnès Baude, Hillel Adesnik, Michel Aimé Picardo, Jean-Claude Platel, Valentina Emiliani, David Angulo-Garcia, Rosa Cossart Nat Neurosci 2023 Sep;26(9):1555-1565. doi: 10.1038/s41593-023-01405-5. Epub 2023 Aug 31.

All-optical recreation of naturalistic neural activity with a multifunctional transgenic reporter mouse Hayley A Bounds, Masato Sadahiro, William D Hendricks, Marta Gajowa, Karthika Gopakumar, Daniel Quintana, Bosiljka Tasic, Tanya L Daigle, Hongkui Zeng, Ian Antón Oldenburg, Hillel Adesnik Cell Rep 2023 Aug 29;42(8):112909. doi: 10.1016/j.celrep.2023.112909. Epub 2023 Aug 4

Cortical VIP neurons locally control the gain but globally control coherence of gamma band rhythms Julia Veit, Gregory Handy, Daniel P Mossing, Brent Doiron, Hillel Adesnik Neuron. 2023 Feb 1;111(3):405-417.e5. doi: 10.1016/j.neuron.2022.10.036. Epub 2022 Nov 15.

The logic of recurrent circuits in the primary visual cortexIan Antón Oldenburg,William D. Hendricks, Gregory Handy, Kiarash Shamardani, HayleyA. Bounds,Brent Doiron, Hillel Adesnik Nature Neuroscience, In press. doi: https://doi.org/10.1101/2022.09.20.508739

Multifunctional Cre-dependent transgenic mice for high-precision all-optical interrogation of neural circuits Hayley A. Bounds, Masato Sadahiro, William D. Hendricks, Marta Gajowa, Ian Antón Oldenburg, Karthika Gopakumar, Daniel Quintana, Bosiljka Tasic, Tanya L. Daigle, Hongkui Zeng, Hillel Adesnik Cell Reports, In press

Cortical VIP neurons locally control the gain but globally control the coherence of gamma band rhythms Julia Veit, Gregory Handy, Daniel P. Mossing, Brent Doiron, Hillel Adesnik Neuron2023 Feb 1;111(3):405-417.e5.doi: 10.1016/j.neuron.2022.10.036. Epub 2022 Nov 15.PMID: 36384143 PMCID: PMC9898108 (available on )

Yi Xue, Laura Waller, Hillel Adesnik, Nicolas Pégard Elife. 2022 Feb 14;11:e73266. doi: 10.7554/eLife.73266. PMID: 35156923 Free PMC article.

Savitha Sridharan, Marta Gajowa, Mora B. Ogando, Uday Jagadisan, Lamiae Abdeladim, Masato Sadahiro, Hayley Bounds, William D. Hendricks, Ian Tayler, Karthika Gopakumar, Ian Antón Oldenburg, Stephen G. Brohawn, Hillel Adesnik Neuron. 2022 Jan 27:S0896-6273(22)00008-3. doi: 10.1016/j.neuron.2022.01.008. Online ahead of print. PMID: 35120626 Free article.

Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs Kyle Tucker, Savitha Sridharan, Hillel Adesnik, Stephen G. Brohawn Nat Commun.2022 Aug 17;13(1):4842. doi: 10.1038/s41467-022-32441-7.PMID: 35977941 PMCID: PMC9385719DOI: 10.1038/s41467-022-32441-7

Evan H. Lyall, Daniel P. Mossing, Scott R. Pluta, Amir Dudai, Hillel Adesnik Elife. 2021 Nov 1;10:e62687. doi: 10.7554/eLife.62687.

Probing neural codes with two-photon holographic optogenetics. Adesnik H, Abdeladim L.Nat Neurosci. 2021 Oct;24(10):1356-1366. doi: 10.1038/s41593-021-00902-9. Epub 2021 Aug 16. PMID: 34400843 Review.

integration during active tactile sensation drives orientation perception. Brown J, Oldenburg IA, Telian GI, Griffin S, Voges M, Jain V, Adesnik H. Neuron. 2021 Mar 30:S0896-6273(21)00190-2. doi: 10.1016/j.neuron.2021.03.020.

Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane. Sorum B, Rietmeijer RA, Gopakumar K, Adesnik H, Brohawn SG.Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2006980118. doi: 10.1073/pnas.2006980118.

Precision multidimensional neural population code recovered from single intracellular recordings. Johnson JK, Geng S, Hoffman MW, Adesnik H, Wessel R.Sci Rep. 2020 Sep 29;10(1):15997. doi: 10.1038/s41598-020-72936-1.

Cell Type-Specific Optogenetic Dissection of Brain Rhythms.Adesnik H.Trends Neurosci. 2018 Mar;41(3):122-124. doi: 10.1016/j.tins.2018.01.001.PMID: 29499773 Review.

Complementary networks of cortical somatostatin interneurons enforce layer specific control. Naka A, Veit J, Shababo B, Chance RK, Risso D, Stafford D, Snyder B, Egladyous A, Chu D, Sridharan S, Mossing DP, Paninski L, Ngai J, Adesnik H. Elife. 2019 Mar 18;8. pii: e43696. doi: 10.7554/eLife.43696.

Superficial Layers Suppress the Deep Layers to Fine-tune Cortical Coding. Pluta SR, Telian GI, Naka A, Adesnik H.J Neurosci. 2019 Mar 13;39(11):2052-2064. doi: 10.1523/JNEUROSCI.1459-18.2018. Epub 2019 Jan 16.

Cracking the Function of Layers in the Sensory Cortex. Adesnik H, Naka A Neuron. 2018 Dec 5;100(5):1028-1043. doi: 10.1016/j.neuron.2018.10.032. Review.

Precise multimodal optical control of neural ensemble activity. Mardinly AR, Oldenburg IA, Pégard NC, Sridharan S, Lyall EH, Chesnov K, Brohawn SG, Waller L, Adesnik H. Nat Neurosci. 2018 Jun;21(6):881-893. doi: 10.1038/s41593-018-0139-8

A neural circuit for gamma-band coherence across the retinotopic map in mouse visual cortex. Hakim RH, Shamardani K, Adesnik H. eLife. 2018 Feb 26;7. doi: 10.7554/eLife.28569.

Layer-specific excitation/inhibition balances during neuronal synchronization in the visual cortex. Adesnik H. J Physiology 2018 Jan 5. doi: 10.1113/JP274986.

Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT). Pegard NC, Mardinly AR, Oldenburg IA, Sridharan S, Walller L, Adesnik H. Nature communications 2017 Oct 31;8(1):1228.

Synaptic Mechanisms of Feature Coding in the Visual Cortex of Awake Mice. Adesnik H. Neuron 2017 Aug 30;95(5):1147-1159

Cortical gamma band synchronization through somatostatin interneurons. Veit J, Hakim R, Jadi MP, Sejnowski TJ, Adesnik H Nature Neuroscience 2017 May 8. Jul;20(7):951-959.

Surround Integration Organizes a Spatial Map during Active Sensation. Pluta SR, Lyall EH, Telian GI, Ryapolova-Webb E, Adesnik H Neuron 2017 Jun 21;94(6):1220-1233.e5

Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons. Mardinly AR, Spiegel I, Patrizi A, Centofante E, Bazinet JE, Tzeng CP, Mandel-Brehm C, Harmin DA, Adesnik H, Fagiolini M, Greenberg ME. Nature. 2016 Mar 17;531(7594):371-5

Compressive light-field microscopy for 3D neural activity recording Pégard NC, Liu HY, Antipa N, Gerlock M, Adesnik H, Waller L. Optica 2016 3 (5), 517-52

Bayesian methods for event analysis of intracellular currents. Josh Merel*, Ben Shababo*, Alex Naka, Hillel Adesnik, Liam Paninski. Journal of Neuroscience Methods 269, 201610.1016/j.jneumeth.2016.05.015

Inhibitory Circuits in Cortical Layer 5. Naka A, Adesnik H. Front Neural Circuits. 2016 May 6;10:35. doi: 10.3389/fncir.2016.0003

A direct translaminar inhibitory circuit tunes cortical output. Pluta S, Naka A, Veit J, Telian G, Hakim R, Taylor D, Yao L, Adesnik H. Nature Neuroscience. 2015 2015 Nov;18(11):1631-40

A Comprehensive Optogenetic Pharmacology Toolkit for In Vivo Control of GABA(A) Receptors and Synaptic Inhibition. Lin WC, Tsai MC, Davenport C, Smith C, Veit J, Wilson N, Adesnik H, Kramer RH. Neuron, 2015 Dec 2;88(5):879-91.

Optogenetic pharmacology for control of native neuronal signaling proteins. Kramer RH, Mourot A, Adesnik H. Nature Neuroscience 2013 Jul;16(7):816-23.

A neural circuit for spatial summation in visual cortex. Adesnik H, Bruns W, Taniguchi H, Huang ZJ, Scanziani M. Nature. 2012 Oct 11;490(7419):226-31.

Gain control by layer six in cortical circuits of vision. Olsen SR, Bortone DS, Adesnik H, Scanziani M. Nature. 2012 Feb 22;483(7387):47-52

Lateral competition for cortical space by layer-specific horizontal circuits. Adesnik H, Scanziani M. Nature. 2010 Apr 22;464(7292):1155-60.

NMDA receptors inhibit synapse unsilencing during brain development. Adesnik H, Li G, During MJ, Pleasure SJ, Nicoll RA. PNAS. 2008 Apr 8;105(14):5597-602.

Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission. Fukata Y, Adesnik H, Iwanaga T, Bredt DS, Nicoll RA, Fukata M. Science. 2006 Sep 22;313(5794):1792-5.

Photoinactivation of native AMPA receptors reveals their real-time trafficking. Adesnik H, Nicoll RA, England PM. Neuron. 2005 Dec 22;48(6):977-85.

Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Tomita S, Adesnik H, Sekiguchi M, Zhang W, Wada K, Howe JR, Nicoll RA, Bredt DS. Nature. 2005 Jun 23;435(7045):1052-8. Epub 2005 Apr 27.