Publications

Probing inter-areal computations with a cellular resolution two-photon holographic mesoscope

Lamiae Abdeladim, Hyeyoung Shin, Uday K. Jagadisan, Mora B. Ogando, Hillel Adesnik · Nature Neuroscience in press

Feature-tuned synaptic inputs to somatostatin interneurons drive context-dependent processing

William D. Hendricks, Masato Sadahiro, Daniel Mossing, Julia Veit, Hillel Adesnik · Neuron 114(7):1257-1268.e5

DOI PubMed PDF

Acute requirement for the hippocampus in putatively conscious vision revealed by a mouse model of blindsight

Nikhil Bhatla, Kevin Cheong, Shinya Takahashi, Chris Lay, Maggie Fiedeldey, Ke Liang, Mengxuan Mao, Yun Feng Wu, Shuai Lu, Kathy Yun, Vivek Ganti, Raphael Tsao, Xiaotian Zhang, Karim A. Mohamed, Yujie Chang, Yanna Geng, Changlong Dai, Alex K. Liu, Lwin Y. Mao, Hyungwoo Kim, Varsha Subraveti, Nicholas Mitchell, Nina Y. Jo, Usman Khan, Raquel Anguera-Singla, Zachary E. Weinreich, Hannah E. Willis, Holly Bridge, Michael P. Stryker, Hillel Adesnik · Current Biology

DOI PubMed

Recurrent pattern completion drives the neocortical representation of sensory inference

Hyeyoung Shin, Mora B. Ogando, Lamiae Abdeladim, Uday K. Jagadisan, Saskia Durand, B. Hardcastle, H. Belski, H. Cabasco, H. Loefler, A. Bawany, J. Wilkes, K. Nguyen, L. Suarez, T. Johnson, W. Han, B. Ouellette, C. Grasso, J. Swapp, V. Ha, A. Young, S. Caldejon, A. Williford, C. Kiselycznyk, J. Lecoq, Hillel Adesnik · Nature Neuroscience 28(11):2319-2329

DOI PubMed PDF

Network influence determines the impact of cortical ensembles on stimulus detection

Hayley A. Bounds, Hillel Adesnik · Neuron 113(14):2358-2369.e5

DOI PubMed PDF

Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Marcus A. Triplett, Marta Gajowa, B. Antin, Masato Sadahiro, Hillel Adesnik, Liam Paninski · Nature Neuroscience 28(10):2154-2165

DOI PubMed PDF

The logic of recurrent circuits in the primary visual cortex

Ian Antón Oldenburg, William D. Hendricks, Gregory Handy, Kiarash Shamardani, Hayley A. Bounds, Brent Doiron, Hillel Adesnik · Nature Neuroscience 27(1):137-147

DOI PubMed PDF

Modeling the diverse effects of divisive normalization on noise correlations

O. Weiss, Hayley A. Bounds, Hillel Adesnik, R. Coen-Cagli · PLoS Computational Biology 19(11):e1011667

DOI PubMed PDF

Prominent in vivo influence of single interneurons in the developing barrel cortex

Yannick Bollmann, Laura Modol, Thomas Tressard, Artem Vorobyev, Robin Dard, Sophie Brustlein, Ruth Sims, Imane Bendifallah, Erwan Leprince, Vincent de Sars, Emiliano Ronzitti, Agnès Baude, Hillel Adesnik, Michel Aimé Picardo, Jean-Claude Platel, Valentina Emiliani, David Angulo-Garcia, Rosa Cossart · Nature Neuroscience 26(9):1555-1565

DOI PubMed

All-optical recreation of naturalistic neural activity with a multifunctional transgenic reporter mouse

Hayley A. Bounds, Masato Sadahiro, William D. Hendricks, Marta Gajowa, Karthika Gopakumar, Daniel Quintana, Bosiljka Tasic, Tanya L. Daigle, Hongkui Zeng, Ian Antón Oldenburg, Hillel Adesnik · Cell Reports 42(8):112909

DOI PubMed PDF

Cortical VIP neurons locally control the gain but globally control coherence of gamma band rhythms

Julia Veit, Gregory Handy, Daniel P. Mossing, Brent Doiron, Hillel Adesnik · Neuron 111(3):405-417.e5

DOI PubMed

Three-dimensional multi-site random access photostimulation (3D-MAP)

Yi Xue, Laura Waller, Hillel Adesnik, Nicolas Pégard · eLife 11:e73266

DOI PubMed PDF

High-performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks

Savitha Sridharan, Marta Gajowa, Mora B. Ogando, Uday K. Jagadisan, Lamiae Abdeladim, Masato Sadahiro, Hayley Bounds, William D. Hendricks, Ian Tayler, Karthika Gopakumar, Ian Antón Oldenburg, Stephen G. Brohawn, Hillel Adesnik · Neuron 110(7):1139-1155.e6

DOI PubMed PDF

Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs

Kyle Tucker, Savitha Sridharan, Hillel Adesnik, Stephen G. Brohawn · Nature Communications 13(1):4842

DOI PubMed PDF

Feature-specific inhibitory connectivity augments the accuracy of cortical representations

Mora B. Ogando, Lamiae Abdeladim, Kevin K. Sit, Hyeyoung Shin, Savitha Sridharan, Karthika Gopakumar, Hillel Adesnik · bioRxiv

DOI

Circuit-based understanding of fine spatial scale clustering of orientation tuning in mouse visual cortex

Yu P, Yang Y, Gozel O, Oldenburg I, Dipoppa M, Rossi LF, Miller K, Adesnik H, Ji N, Doiron B · bioRxiv

DOI

Balanced bidirectional optogenetics reveals the causal impact of cortical temporal dynamics in sensory perception

Daniel Quintana, Hayley Bounds, Julia Veit, Hillel Adesnik · bioRxiv

DOI

maskNMF: A denoise-sparsen-detect approach for extracting neural signals from dense imaging data

Amol Pasarkar, Ian Kinsella, Pengcheng Zhou, Melissa Wu, Daisong Pan, Jiang Lan Fan, Zhen Wang, Lamiae Abdeladim, Darcy S. Peterka, Hillel Adesnik, Na Ji, Liam Paninski · bioRxiv

DOI

Dissociating instructive from permissive roles of brain circuits with reversible neural activity manipulations

Daniel Quintana, Hayley A. Bounds, Jennifer Brown, May Wang, Nikhil Bhatla, J. Simon Wiegert, Hillel Adesnik · bioRxiv

DOI

Synthesis of higher order feature codes through stimulus-specific supra-linear summation

Evan H. Lyall, Daniel P. Mossing, Scott R. Pluta, Amir Dudai, Hillel Adesnik · eLife 10:e62687

DOI PubMed PDF

Probing neural codes with two-photon holographic optogenetics

Hillel Adesnik, Lamiae Abdeladim · Nature Neuroscience 24(10):1356-1366

DOI PubMed

Integration during active tactile sensation drives orientation perception

Jennifer Brown, Ian Antón Oldenburg, Gavin I. Telian, Shanley Griffin, Marta Voges, Vivek Jain, Hillel Adesnik · Neuron 109(10):1707-1720.e7

DOI PubMed PDF

Ultrasound activates mechanosensitive TRAAK K+ channels through the lipid membrane

Ben Sorum, Robert A. Rietmeijer, Karthika Gopakumar, Hillel Adesnik, Stephen G. Brohawn · Proceedings of the National Academy of Sciences USA 118(6):e2006980118

DOI PubMed PDF

Precision multidimensional neural population code recovered from single intracellular recordings

Jonathan K. Johnson, S. Geng, Matthew W. Hoffman, Hillel Adesnik, Ralf Wessel · Scientific Reports 10:15997

DOI PubMed PDF

Complementary networks of cortical somatostatin interneurons enforce layer specific control

Alexander Naka, Julia Veit, Ben Shababo, Rebecca K. Chance, Davide Risso, David Stafford, Benjamin Snyder, Andrew Egladyous, Desiree Chu, Savitha Sridharan, Daniel P. Mossing, Liam Paninski, John Ngai, Hillel Adesnik · eLife 8:e43696

DOI PubMed PDF

Superficial layers suppress the deep layers to fine-tune cortical coding

Scott R. Pluta, Gavin I. Telian, Alexander Naka, Hillel Adesnik · Journal of Neuroscience 39(11):2052-2064

DOI PubMed PDF

Cracking the function of layers in the sensory cortex

Hillel Adesnik, Alexander Naka · Neuron 100(5):1028-1043

DOI PubMed PDF

Precise multimodal optical control of neural ensemble activity

Alan R. Mardinly, Ian Antón Oldenburg, Nicolas C. Pégard, Savitha Sridharan, Evan H. Lyall, Kirill Chesnov, Stephen G. Brohawn, Laura Waller, Hillel Adesnik · Nature Neuroscience 21(6):881-893

DOI PubMed

Cell type-specific optogenetic dissection of brain rhythms

Hillel Adesnik · Trends in Neurosciences 41(3):122-124

DOI PubMed

A neural circuit for gamma-band coherence across the retinotopic map in mouse visual cortex

Richard H. Hakim, Kiarash Shamardani, Hillel Adesnik · eLife 7:e28569

DOI PubMed PDF

Layer-specific excitation/inhibition balances during neuronal synchronization in the visual cortex

Hillel Adesnik · Journal of Physiology 596(9):1639-1657

DOI PubMed PDF

Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT)

Nicolas C. Pégard, Alan R. Mardinly, Ian Antón Oldenburg, Savitha Sridharan, Laura Waller, Hillel Adesnik · Nature Communications 8(1):1228

DOI PubMed PDF

Synaptic mechanisms of feature coding in the visual cortex of awake mice

Hillel Adesnik · Neuron 95(5):1147-1159.e4

DOI PubMed PDF

Cortical gamma band synchronization through somatostatin interneurons

Julia Veit, Richard Hakim, Monika P. Jadi, Terrence J. Sejnowski, Hillel Adesnik · Nature Neuroscience 20(7):951-959

DOI PubMed

Surround integration organizes a spatial map during active sensation

Scott R. Pluta, Evan H. Lyall, Gavin I. Telian, Elena Ryapolova-Webb, Hillel Adesnik · Neuron 94(6):1220-1233.e5

DOI PubMed PDF

Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons

Alan R. Mardinly, Ivo Spiegel, Annarita Patrizi, Eleonora Centofante, Janet E. Bazinet, Christopher P. Tzeng, Caroline Mandel-Brehm, David A. Harmin, Hillel Adesnik, Michela Fagiolini, Michael E. Greenberg · Nature 531(7594):371-375

DOI PubMed

Compressive light-field microscopy for 3D neural activity recording

Nicolas C. Pégard, Hsiou-Yuan Liu, Nick Antipa, M. Gerlock, Hillel Adesnik, Laura Waller · Optica 3(5):517-524

DOI

Bayesian methods for event analysis of intracellular currents

Josh Merel, Ben Shababo, Alex Naka, Hillel Adesnik, Liam Paninski · Journal of Neuroscience Methods 269:21-32

DOI PubMed

Inhibitory circuits in cortical layer 5

Alexander Naka, Hillel Adesnik · Frontiers in Neural Circuits 10:35

DOI PubMed PDF

A direct translaminar inhibitory circuit tunes cortical output

Scott Pluta, Alexander Naka, Julia Veit, Gregory Telian, Richard Hakim, David Taylor, Lucy Yao, Hillel Adesnik · Nature Neuroscience 18(11):1631-1640

DOI PubMed

A comprehensive optogenetic pharmacology toolkit for in vivo control of GABA(A) receptors and synaptic inhibition

Wan-Chen Lin, Ming-Chi Tsai, Christopher Davenport, Caleb M. Smith, Julia Veit, Nicole M. Wilson, Hillel Adesnik, Richard H. Kramer · Neuron 88(5):879-891

DOI PubMed PDF

Optogenetic pharmacology for control of native neuronal signaling proteins

Richard H. Kramer, Alexandre Mourot, Hillel Adesnik · Nature Neuroscience 16(7):816-823

DOI PubMed

A neural circuit for spatial summation in visual cortex

Hillel Adesnik, William Bruns, Hiroki Taniguchi, Z. Josh Huang, Massimo Scanziani · Nature 490(7419):226-231

DOI PubMed

Gain control by layer six in cortical circuits of vision

Shawn R. Olsen, Dante S. Bortone, Hillel Adesnik, Massimo Scanziani · Nature 483(7387):47-52

DOI PubMed

Lateral competition for cortical space by layer-specific horizontal circuits

Hillel Adesnik, Massimo Scanziani · Nature 464(7292):1155-1160

DOI PubMed

NMDA receptors inhibit synapse unsilencing during brain development

Hillel Adesnik, Guangnan Li, Matthew J. During, Samuel J. Pleasure, Roger A. Nicoll · Proceedings of the National Academy of Sciences USA 105(14):5597-5602

DOI PubMed

Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission

Yuko Fukata, Hillel Adesnik, Toshihiro Iwanaga, David S. Bredt, Roger A. Nicoll, Masaki Fukata · Science 313(5794):1792-1795

DOI PubMed

Photoinactivation of native AMPA receptors reveals their real-time trafficking

Hillel Adesnik, Roger A. Nicoll, Pamela M. England · Neuron 48(6):977-985

DOI PubMed PDF

Stargazin modulates AMPA receptor gating and trafficking by distinct domains

Susumu Tomita, Hillel Adesnik, Masahiko Sekiguchi, Wei Zhang, Keiji Wada, James R. Howe, Roger A. Nicoll, David S. Bredt · Nature 435(7045):1052-1058

DOI PubMed